Seahorse文献合集(2026.01)-夜雨聆风

Seahorse文献合集(2026.01)

细胞能量代谢是研究与生命现象相伴的活体内能量变化的科学。生物能量学与衰老、癌症、免疫学、神经退行性疾病、糖尿病、肥胖等密切相关。SeahorseXF细胞能量代谢检测技术能够实时、动态地检测细胞的氧气消耗率（OCR）和细胞外酸化率（ECAR），从而精确评估细胞的线粒体功能和糖酵解能力。

佰昊生物提供Seahorse细胞能量代谢检测技术服务，涵盖细胞铺板、上机检测到数据分析全流程，助力加速科研进程。

以下是2026年1月份发表的seahorse文献：

PART.01

癌症研究

1.Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9(+) macrophages via the mTORC1-C/EBPβ-OSM axis. Redox Biol. 2026 Feb;89:103970. doi: 10.1016/j.redox.2025.103970. Epub 2025 Dec 13.

2.Adipocyte fatty acid-binding protein as a cerebrospinal fluid-accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation. Clin Transl Med. 2026 Feb;16(2):e70607. doi: 10.1002/ctm2.70607.

3.Tramadol induced hypoxia signaling and paraptosis-like cell death in breast cancer cells via HIF-1α and ATF4 dependent pathways. Redox Rep. 2026 Dec;31(1):2588866. doi: 10.1080/13510002.2025.2588866. Epub 2026 Jan 12.

4.Berberine facilitates alveolar bone regeneration via Ptgs2-mediated dual regulation of osteoblast differentiation and fibroblast inhibition. Phytomedicine. 2026 Jan;150:157678. doi: 10.1016/j.phymed.2025.157678. Epub 2025 Dec 7.

5.Molecular identifiers of the evolutionarily conserved titin pseudokinase. Biochem J. 2026 Jan 7;483(1):55-70. doi: 10.1042/BCJ20253442.

6.Parental fasting effects on offspring immune gene expression, epigenetic patterns, and gut microbiota in a species with male pregnancy (Syngnathus typhle). BMC Biol. 2026 Jan 14;24(1):24. doi: 10.1186/s12915-026-02509-7.

7.Sexual receptivity increases in synchrony with the ovulatory cycle in female medaka. J Neuroendocrinol. 2026 Jan;38(1):e70119. doi: 10.1111/jne.70119.

8.Shared and Unique Patterns of Genomic Differentiation and Introgression Between Japanese Stickleback Species Across Three Sympatric Sites. Mol Ecol. 2026 Jan;35(2):e70249. doi: 10.1111/mec.70249.

9.Assessing movement patterns of the highly invasive western mosquitofish (Gambusia affinis). Proc Biol Sci. 2026 Jan 7;293(2062):20251954. doi: 10.1098/rspb.2025.1954.

PART.02

线粒体研究

1.Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization. Adv Sci (Weinh). 2026 Jan;13(6):e14514. doi: 10.1002/advs.202514514. Epub 2025 Nov 14.

2.Perfluorooctane sulfonic acid (PFOS) perturbs skeletal muscle oxidative phosphorylation by a different mechanism than liver. Chemosphere. 2026 Feb;394:144815. doi: 10.1016/j.chemosphere.2025.144815. Epub 2025 Dec 30.

3.SIAH2-WNK1 Signaling Drives Glycolytic Metabolism and Therapeutic Resistance in Colorectal Cancer. Int J Mol Sci. 2026 Jan 21;27(2):1065. doi: 10.3390/ijms27021065.

4.DNA Hypermethylation-induced LRRC4 downregulation: a driver of glycolysis and lung adenocarcinoma progression. Integr Biol (Camb). 2026 Jan 16;18:zyag002. doi: 10.1093/intbio/zyag002.

5.An evolutionary shift to prioritizing mating over care is associated with consistently high androgen levels in male threespine stickleback. Horm Behav. 2026 Jan;177:105866. doi: 10.1016/j.yhbeh.2025.105866. Epub 2025 Dec 13.

6.Witnessing others interact with a novel object has sex- and size-specific effects on neophilia in mosquitofish. Behav Processes. 2026 Jan;234:105308. doi: 10.1016/j.beproc.2025.105308. Epub 2025 Nov 20.

7.New species of the genus Skrjabinolecithum (Digenea: Haploporidae) from the mullets in Russia, the Far East, and Vietnam: morphology and molecular data. Syst Parasitol. 2026 Jan 17;103(1):3. doi: 10.1007/s11230-025-10260-w.

8.Effects of cyp19a1a and cyp19a1b Knockout on Germ Cell Kinetics During Gonadal Sex Differentiation in Medaka. Dev Growth Differ. 2026 Jan;68(1):e70038. doi: 10.1111/dgd.70038.

PART.03

免疫研究

1.PTPN22 as a therapeutic target in intervertebral disc degeneration: Modulating mitophagy and pyroptosis through the PI3K/AKT/mTOR axis. J Adv Res. 2026 Feb;80:775-789. doi: 10.1016/j.jare.2025.05.017. Epub 2025 May 9.

2.Brg1-imprinted chromatin status controls effector and memory group 2 innate lymphoid cell metabolism to exacerbate allergic lung inflammation. J Allergy Clin Immunol. 2026 Jan;157(1):155-175. doi: 10.1016/j.jaci.2025.08.029. Epub 2025 Sep 17.

3.YTHDF2-mediated stabilization of SREBF1 promotes lipid metabolic reprogramming and ferroptosis-associated radioresistance in anaplastic thyroid carcinoma. Cancer Lett. 2026 Feb 28;639:218232. doi: 10.1016/j.canlet.2025.218232. Epub 2025 Dec 21.

4.Brain-derived estrogens facilitate male-typical behaviors by potentiating androgen receptor signaling in medaka. Elife. 2026 Jan 13;13:RP97106. doi: 10.7554/eLife.97106.

5.Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity. Front Immunol. 2026 Jan 7;16:1685796. doi: 10.3389/fimmu.2025.1685796. eCollection 2025.

6.Dysfunctional T cells due to the abnormal glucose metabolism in patients with primary immune thrombocytopenia. Br J Haematol. 2026 Jan;208(1):129-138. doi: 10.1111/bjh.70229. Epub 2025 Nov 7.

PART.04

神经研究

1.ASIC3-PLCG1 axis-driven macropinocytosis promotes osimertinib drug-tolerant persistence in malignant pleural effusion-associated NSCLC. Eur J Pharm Sci. 2026 Feb 1;217:107417. doi: 10.1016/j.ejps.2025.107417. Epub 2025 Dec 17.

2.Non-parallel impacts of predators on the evolution of coloration plasticity in Trinidadian killifish. Evolution. 2026 Jan 28;80(1):216-229. doi: 10.1093/evolut/qpaf218.

3.Influences of Size-Selective Harvesting on Growth Characteristics and Associated Gene Expression Patterns in Marine Medaka (Oryzias melastigma). Mar Biotechnol (NY). 2026 Jan 9;28(1):16. doi: 10.1007/s10126-025-10566-2.

PART.05

其他

1.Ecotoxicological insights into UV-P-induced immunotoxicity and bacterial infection risk in marine medaka (Oryzias melastigma). Environ Res. 2026 Mar 1;292:123733. doi: 10.1016/j.envres.2026.123733. Epub 2026 Jan 8.

2.Covalent targeting GAPDH by Pudilan formula and baicalein suppresses macrophage Warburg effect to alleviate acute lung injury. Phytomedicine. 2026 Feb;151:157727. doi: 10.1016/j.phymed.2025.157727. Epub 2025 Dec 21.

3.Integrative toxicity characterization of gamma alumina-based nanomaterials on a native fish Cnesterodon decemmaculatus (Pisces: Poeciliidae). Environ Toxicol Chem. 2026 Jan 1;45(1):126-136. doi: 10.1093/etojnl/vgaf256.

4.Quantitative proteomics links mitochondrial dysfunction to metabolic changes and epithelial differentiation defects in hyperoxia-exposed neonatal airway cells. Am J Physiol Lung Cell Mol Physiol. 2026 Jan 1;330(1):L87-L103. doi: 10.1152/ajplung.00205.2025. Epub 2025 Dec 5.

5.Significant spatial shifting of the eukaryotic plankton community in a small-scale fish-killing harmful algal bloom of Prorocentrum and Karenia near Huangqi Peninsula, Lianjiang, Fujian, China. Mar Environ Res. 2026 Mar;215:107819. doi: 10.1016/j.marenvres.2025.107819. Epub 2025 Dec 27.

6.Darkness modifies brain cell proliferation and behavior in female Austrolebias reicherti fish. J Exp Biol. 2026 Jan 1;229(1):jeb251364. doi: 10.1242/jeb.251364. Epub 2026 Jan 2.

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